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This volume covers the topics presented at the 3rd International Conference on Tumor Microenvironment and Cellular Stress by an international community of researchers. The conference brings together scientists to discuss different cellular and animal models of tumor microenvironment study and identify common pathways that are candidates for therapeutic intervention; stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology (e.g., HIF regulation) and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery; and critically evaluate novel targets for imaging or therapeutic intervention that would be of use to the tumor microenvironment community and pharmaceutical industry. Intratumor Heterogeneity and Branched Evolution Revealed Background Intratumor heterogeneity may foster tumor evolution and adaptation and hinder personalized-medicine strategies that depend on results from single tumor Chimeric Antigen Receptor T Cells for Sustained Remissions Original Article Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia Shannon L Maude MD PhD Noelle Frey MD Pamela A Shaw PhD Supercourse: Epidemiology the Internet and Global Health This course is designed to provide an overview on epidemiology and the Internet for medical and health related students around the world based on the concept of Colorectal Cancer Biomarkers and the Potential Role of J Cancer 2013; 4(3):241-250 doi:107150/jca5832 Review Colorectal Cancer Biomarkers and the Potential Role of Cancer Stem Cells Russell C Langan 1 John E Targeted Molecular Therapy in Head and Neck Squamous Cell With the increased understanding of molecular mechanisms and basic pathways in the pathogenesis of squamous cell cancer of the head and neck these
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